Isabelle's circle of friends included Clary, Alec, and Clary's boyfriend Jace. Isabelle worked as a developer for the Institute, a company ran by Clary's father Valentine Morgenstern, her boss whom she harbors a bit of a crush on. The Institute held an anniversary party planned by Alec. On the day of the party, Isabelle received a big black eye during her kickboxing class and, in a panic, called Clary to help cover it up. At the party, Isabelle entertained guests and briefed some with Valentine. Later, she danced with Simon, who planned to ask her to move in with him.
- A big difference from her alternate dimension counterpart is that this Isabelle, due to not living the life of a Shadowhunter, is somewhat of a geek.
- 1x10: This World Inverted (first and only appearance)